Izvorni znanstveni članak
Effect of hyoscine-N-butyl bromide rectal suppository on labor progress in primigravid women: randomized doubleblind placebo-controlled clinical trial
Somayeh Makvandi
; Department of Midwifery, Faculty of Nursing and Midwifery, Ahvaz Azad University, Ahvaz, Iran
Mitra Tadayon
; Department of Midwifery, Faculty of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Mohammadreza Abbaspour
; Nanotechnology Research Center and School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Sažetak
Aim To determine the effects of hyoscine-N-butyl bromide
(HBB) rectal suppository on labor progress in primigravid
women.
Methods A randomized double-blind placebo-controlled
clinical trial was carried out on 130 primigravid women admitted for spontaneous labor. The women were recruited based on the inclusion and exclusion criteria and randomized into the experimental (n = 65) and control group
(n = 65). In the beginning of the active phase of labor, 20
mg of HBB rectal suppository was administered to the experimental group, while a placebo suppository was administered to the control group. Cervical dilatation and
duration of active phase and second stage of labor were
recorded.
Results The rate of cervical dilatation was 2.6 cm/h in the
experimental and 1.5 cm/h in the control group (P < 0.001).
The active phase and the second stage of labor were significantly shorter in the experimental group (P = 0.001 and
P < 0.001, respectively). There was no significant difference
between the two groups in the fetal heart rate, maternal
pulse rate, blood pressure, and the APGAR score 1 and 5
minutes after birth.
Conclusion Use of HBB rectal suppository in the active
management of labor can shorten both the active phase
and second stage of labor without significant side-effects.
Ključne riječi
Hrčak ID:
71427
URI
Datum izdavanja:
15.4.2011.
Posjeta: 2.119 *