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Obesity in Type 2 Diabetes: Prevalence, Treatment Trends and Dilemmas

Tamara Poljičanin
Ivana Pavlić-Renar
Željko Metelko


Puni tekst: engleski pdf 143 Kb

str. 829-834

preuzimanja: 616

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Sažetak

This retrospective observational study investigated the prevalence of obesity in persons with type 2 diabetes, trends in
obesity resulting from the duration and treatment of diabetes, and treatment-related changes in HbA1c and body mass
index (BMI). Data on 1773 type 2 diabetics (802 men and 971 women) were obtained from the CroDiabNET registry. Follow-
up included the analysis of patients’ age, disease duration, diabetes treatment, BMI and HbA1c values. A significantly
higher rate of overweight and obesity was found in persons with type 2 diabetes as compared to the general population.
A significant decrease in BMI was observed in the groups treated by diet, and in those treated by oral hypoglycaemic
agents (p<0.05), regardless of their pharmacotherapeutic group, in contrast to a significant increase in BMI observed in
the groups treated with insulin (alone or in combination with oral hypoglycaemic agents) (p<0.05). Persons with type 2
diabetes lost weight only during the first years of the disease, while with diabetes duration and insulin treatment they regained
weight. A significant increase in HbA1c was observed in the groups treated with sulfonylureas (p<0.05), whereas
all other groups revealed either a significant decrease (p<0.05) or no change in HbA1c. Our findings suggest the necessity
of an integrated approach to managing type 2 diabetic patients that would simultaneously address both diabetes and
obesity. Good glycaemic control is imperative and diabetes treatment should not be postponed. Because of a possible concomitant
weight gain, aggressive weight control measures should be applied concurrently in order to achieve maximum
treatment benefit.

Ključne riječi

diabetes mellitus, epidemiology, obesity, overweight, prevalence, weight gain

Hrčak ID:

72181

URI

https://hrcak.srce.hr/72181

Posjeta: 963 *