Preliminary communication
Resolution of Pseudophakic Cystoid Macular Edema with Combination Therapy of Topical Corticosteroids and Nonsteroidal Anti-inflammatory Drugs
Ivana Romac
Nikica Gabrić
Iva Dekaris
Ante Barišić
Abstract
A 69 years old women underwent uneventful cataract surgery of her left eye with phacoemulsification and posterior
chamber intraocular lens implantation in topical anesteshia. Patinet was postoperatively treated with combination of antibiotic
and steroid in decreasing dosages during five weeks: one drop five times a day the first week, three times a day
second to forth week and one time a day the fifth week. In each checkup, performed first postoperative day, 7 days, 5 weeks
and 12 weeks after the operation, visual acuity with and without correction, tonometry, corneal transparency, biomicroscopy
of posterior pole and measure of macular thickness by optical coherence tomography (OCT) were performed. At first
day follow-up visit, the patient’s visual acuity was 20/25 but 6 weeks after the operation, the patient’s vision had worsened
to 20/60 after a slow steroid tapper. At that time OCT showed foveal thickening and cystic changes specific for
cystoid macular edema (CME). Combination of corticosteroid and non-steroidal anti-inflammatory drug four times
daily was included in therapy. The dose was tapered off over the ensuing 8 weeks. The total treatment duration was 12
weeks. At the patient’s 2-month follow-up visit, vision has improved to 20/20 and the fovea appeared flat. OCT showed
complete resolution of foveal thickening and cystic changes. Combination of corticosteroid and NSAID is effective and
safe therapy for treating pseudophakic CME. Patient showed significant improvement in visual acuity and retinal thickness
at 2 months post treatment.
Abbreviations: OCT – optical coherence tomography, CME – cystoid macular edema, NSAID – non-steroidal anti-inflammatory
drugs
Keywords
cystoid macular edema; corticosteroids; antibiotics; non-steroidal anti-inflammatory drug; optical coherence tomography
Hrčak ID:
72291
URI
Publication date:
25.9.2011.
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