Conference paper

REINFORCEMENT OF IRRITABILITY DURING THERAPY WITH BENZODIAZEPINES

Suzana Uzun ; University Department, Vrapče Psychiatric Hospital, Zagreb, Croatia
Oliver Kozumplik ; University Department, Vrapče Psychiatric Hospital, Zagreb, Croatia

Abstract

Background: Often, long-term treatment with benzodiazepines is a subject of discussion due to potential side effects, with
dependence on benzodiazepines as the most serous one. After longer period of benzodiazepines tolerance on their anxiolytic effects
develops. Discontinuation is usually beneficial as it is followed by improved psychomotor and cognitive functioning, particularly in
the elderly. Previous studies confirmed occurrence of physical dependence in high percentage of patients in long term treatment with benzodiazepines at therapeutic dosages. Benzodiazepines are relatively well-tolerated medicines but can induce serious problems of
addiction and that is why their use is regulated. The aim of this article is to report a case of a patient who was taking 15 tablets of
oxazepam daily for a period of time, during which reinforcement of irritability occurred.
Conclusion: It is necessary to warn patients who take benzodiazepines in therapy that reinforcement of irritability may occur in case of higher dosage of benzodiazepines, which may be misinterpreted as worsening in mental condition.

Keywords

benzodiazepines; irritability; oxazepam; dependence

Hrčak ID:

76807

URI

https://hrcak.srce.hr/76807

Publication date:

31.3.2011.

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