Original scientific paper
Trends in lung cancer incidence and mortality in Croatia, 1988-2008
Mateja Janković
; Department for Respiratory Diseases University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
Miroslav Samaržija
; Department for Respiratory Diseases University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
Marko Jakopović
; Department for Respiratory Diseases University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
Tomislav Kuliš
; Department of Urology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia
Ariana Znaor
; Croatian National Cancer Registry, Croatian National Institute of Public Health, Zagreb, Croatia
Abstract
Aim To describe and interpret lung cancer incidence and
mortality trends in Croatia between 1988 and 2008.
Methods Incidence data on lung cancer for the period
1988-2008 were obtained from the Croatian National Cancer
Registry, while mortality data were obtained from the
World Health Organization mortality database. Population
estimates for Croatia were obtained from the Population
Division of the Department of Economic and Social Affairs
of the United Nations. We also calculated and analyzed
age-standardized incidence and mortality rates. To describe
time incidence and mortality trends, we used joinpoint
regression analysis.
Results Lung cancer incidence and mortality rates in men
decreased significantly in all age groups younger than 70
years. Age-standardized incidence rates in men decreased
significantly by -1.3% annually. Joinpoint analysis of mortality
in men identified three trends, and average annual percent
change (AAPC) decreased significantly by -1.1%. Lung
cancer incidence and mortality rates in women increased
significantly in all age groups older than 40 years and decreased
in younger women (30-39- years). Age-standardized
incidence rates increased significantly by 1.7% annually.
Joinpoint analysis of age-standardized mortality rates
in women identified two trends, and AAPC increased significantly
by 1.9%.
Conclusion Despite the overall decreasing trend, Croatia
is still among the European countries with the highest
male lung cancer incidence and mortality. Although the
incidence trend in women is increasing, their age standardized
incidence rates are still 5-fold lower than in men.
These trends follow the observed decrease and increase in
the prevalence of male and female smokers, respectively.
These findings indicate the need for further introduction
of smoking prevention and cessation policies targeting
younger population, particularly women.
Keywords
Hrčak ID:
82898
URI
Publication date:
15.4.2012.
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