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Clear Cell Variant of Urothelial Carcinoma in Urinary Bladder; a Clinicopathological and Immunohistochemical Study – A Case Report

Zoran Peršec ; University of Zagreb, Dubrava University Hospital, Department of Urology, Zagreb, Croatia
Damir Buković ; University of Zagreb, Zagreb University Hospital Center, Department of Obstetrics and Gynecology, Zagreb, Croatia
Jasminka Peršec ; University of Zagreb, Dubrava University Hospital, Anesthesiology, Resuscitation and Intensive Care Medicine Clinic,
Duje Rako ; University of Zagreb, Dubrava University Hospital, Department of Urology, Zagreb, Croatia
Danica Ljubanović ; University of Zagreb, Dubrava University Hospital, Department of Pathology, Zagreb, Croatia
Vito Starčević ; University of Zagreb, Zagreb University Hospital Center, Department of Obstetrics and Gynecology, Zagreb, Croatia
Tomislav Župić ; University of Zagreb, Zagreb University Hospital Center, Department of Obstetrics and Gynecology, Zagreb, Croatia
Mato Pavić ; University of Zagreb, Zagreb University Hospital Center, Department of Obstetrics and Gynecology, Zagreb, Croatia


Puni tekst: engleski pdf 1.565 Kb

str. 1045-1047

preuzimanja: 580

citiraj


Sažetak

The clear cell variant urothelial carcinoma of urinary bladder is very rare and unusual neoplasm defined histologically by clear cell pattern and glycogen–rich cytoplasm. Our case of clear cell carcinoma was diagnosed with immunohistochemistry stain. A 72-year-old man, presented with painless macroscopic hematuria in November 2007. Evaluation revealed papillary tumor in urinary bladder. A transurethral resection of the bladder tumor (TUR-Bt) was performed.
Histopatologic evaluation showed superficial transitional cell carcinoma and carcinoma in situ. On three month follow-up, a solitary pedunculated tumor was detected again in the left wall of the urinary bladder. A repeated transurethral resection of the bladder tumor (reTUR-Bt) was performed in February 2008. The pathological diagnosis was difficult due to diffuse clear cell appearance. Immunohistochemistry stain showed urothelial carcinoma and finally it
was diagnosed as clear cell variant. Urothelial carcinoma has many variants that show a variety of appearances and characteristics. These should be well known for evaluation and optimal treatment.

Ključne riječi

clear cell variant of urothelial carcinoma, urinary bladder, immunohistochemistry stain

Hrčak ID:

90950

URI

https://hrcak.srce.hr/90950

Posjeta: 886 *