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Carotid Intima-Media Thickness in Patients with Chronic and Aggressive Periodontitis

Ivan Puhar ; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Zagreb, Hrvatska
Arijana Lovrenčić-Huzjan ; Klinički zavod za neurologiju Kliničkog bolničkog centra “Sestre milosrdnice“, Zagreb, Hrvatska
Darja Šodec-Šimičević ; Klinički zavod za neurologiju Kliničkog bolničkog centra “Sestre milosrdnice“, Zagreb, Hrvatska
Maja Strineka ; Klinički zavod za dijagnostičku i intervencijsku radiologiju, Klinička bolnica Dubrava, Zagreb
Darko Božić ; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Zagreb, Hrvatska
Darije Plančak ; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu i Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Zagreb, Hrvatska

Sažetak

Objective: The objective of this study was to investigate the elationship between carotid intima-media thickness (IMT) and periodontal status in periodontitis patients. Materials and methods:
The study was conducted on 128 subjects divided into four groups. The test groups consisted of 37 patients with chronic periodontitis (18 men and 19 women, mean age 57.2±8.0 years) and 30 patients with aggressive periodontitis (13 men and 17 women, mean age 34.7±6.3 years). There were 27 subjects in the control group for chronic periodontitis (11 men and 16 women, mean age 53.0±10.1 years), and 34 subjects in the control group for aggressive periodontitis (15 men and 19 women, mean age 27.7±5.7 years). Both control groups consisted of periodontally healthy volunteers. Periodontal condition was assessed using periodontal indices. Triglycerides, HDL cholesterol, LDL cholesterol, total serum cholesterol, high sensitive C-reactive protein (hsCRP), and glucose levels were quantified in serum. IMT measurements on common carotid artery were performed using Aloka ProSound ALPHA 10 with 13 MHz linear probe. Results: This research revealed significantly higher values of overall (0.8 mm) and right (0.8 mm) carotid IMT in chronic periodontitis patients only. Chronic periodontitis was a statistically significant predictor (p=0,003) for the right carotid IMT in the multivariate model, when potentially confounding factors were included. Both periodontitis groups mainly included nonsmokers, and had statistically higher levels of hsCRP (2.2 and 1.4 mg/L). Conclusions: The study demonstrated that chronic periodontitis can be linked with carotid atherosclerosis, but further research is required for a more precise assessment of the influence of aggressive periodontitis on carotid IMT.

Ključne riječi

Periodontitis; Periodontal Index; Carotid Stenosis; Tunica Intima; C-Reactive Protein

Hrčak ID:

94352

URI

https://hrcak.srce.hr/94352

Datum izdavanja:

28.12.2012.

Podaci na drugim jezicima: hrvatski

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