Izvorni znanstveni članak

https://doi.org/10.5562/cca2125

ESI MS/MS Study of Calix[4]arene Derivatives and their Metal Complexes

Tomislav Benković ; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000 Zagreb, Croatia
Vladislav Tomišić ; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000 Zagreb, Croatia
Leo Frkanec ; Department of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička c. 54, HR-10000 Zagreb, Croatia
Nives Galić orcid.org/0000-0002-0958-1791 ; Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, HR-10000 Zagreb, Croatia

Sažetak

The peptidocalixarenes 1–3 bearing tryptophan, phenylglycine and leucil units at the lower rim and their complexes with alkali-metal (Li+, Na+, K+, Rb+, Cs+) and selected lanthanide cations (La3+, Ce3+, Eu3+, Yb3+) were analyzed by ESI MS. The influences of the solvent (acetonitrile, methanol, addition of formic acid or sodium acetate) and the calixarene:cation molar ratio on signal intensities were investigated. Comprehensive MS/MS analyses were performed of all singly and doubly charged ions of 1–3 and their complexes, and fragmentation pathways were proposed. An inductive cleavage was observed during dissociation of protonated ions, while the presence of alkali-metal or lanthanide cations caused homolytic cleavage and formation of radical cations. The results of MS analysis were in accordance with those ob-tained by other techniques (spectrophotometric, potentiometric, and conductometric titrations). The MS/MS experiments could be used as fast and sensitive method for prediction of relative stabilities of ca-lixarene complexes with metal ions. (doi: 10.5562/cca2125)

Ključne riječi

calixarenes; alkali-metal cations; lanthanides; electrospray; mass spectrometry

Hrčak ID:

94444

URI

https://hrcak.srce.hr/94444

Datum izdavanja:

17.12.2012.

Posjeta: 3.245 *