Pregledni rad

https://doi.org/10.5562/cca2124

Benzotriazole as a Synthetic Auxiliary

Branka Zorc orcid.org/0000-0003-4355-8816 ; Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia
Zrinka Rajić Džolić ; Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia
Ivan Butula ; Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia

Sažetak

Benzotriazole is a very useful synthetic auxiliary with versatile applications in organic chemis¬try. We have used benzotriazole in the synthesis of various heterocyclic compounds (benzoxazine, quinazoline, triazinetrione, hydantoin, oxadiazine and diazepane derivatives), amino acid derivatives, car¬bamates, ureas, semicarbazides, carbazides, sulfonylureas, sulfonylcarbazides, hydantoic acids, non-steroidal antiinflammatory drug (NSAID) and primaquine derivatives, polymer-drug and thiomer-drug conjugates. The results have been published in more than 30 papers and here we give an overview of all syntheses. (doi: 10.5562/cca2124)

Ključne riječi

benzotriazole, 1-benzotriazole carboxylic acid chloride, synthesis, heterocyclic compound, amino acid, NSAID, primaquine, polymer-drug conjugate

Hrčak ID:

94472

URI

https://hrcak.srce.hr/94472

Posjeta: 2.063 *