Ostalo
Treatment of Scabies: Comparison of Ivermectin vs. Lindane Lotion 1%
Alireza Mohebbipour
Parviz Saleh
Mohamad Goldust
; Student Research Committee Tabriz University of Medical Sciences Tabriz Iran
Mehdi Amirnia
Yousef Javad Zadeh
Ramin Mir Mohamadi
Elham Rezaee
Sažetak
Topical antiscabietics have poor compliance. This study aimed at
comparing the efficacy and safety of oral ivermectin with topical lindane in treating
scabies. In this clinical trial, 248 patients from 2 to 86 years of age were divided
into two groups. Oral ivermectin was given to group A in a single dose of
200 μg/kg body weight. Group B received application of lindane lotion 1% twice
at one-week interval. When there was no cure in two weeks, 2nd treatment was
given with either drug in the respective group. A single dose of ivermectin provided
a cure rate of 58.6% at two-week follow up, which increased to 92.7% with
2 doses at the end of 4-week interval. The application of lindane lotion 1% twice
at one-week interval was effective in 44.3% of patients at two-week follow up,
which increased to 71.7% after repeating the treatment for another two weeks.
Single dose application of oral ivermectin was as effective as twice application of
lindane lotion 1% at one-week interval. Two doses of ivermectin proved superior
to lindane lotion 1% after repeating the treatment at 4-week follow up.
Ključne riječi
scabies; lindane lotion 1%; oral ivermectin
Hrčak ID:
95698
URI
Datum izdavanja:
11.1.2013.
Posjeta: 813 *