Kratko priopćenje

A ROLE OF WNT IN KIDNEY DEVELOPMENT AND FUNCTION

INES MESAR ; Zavod za nefrologiju, arterijsku hipertenziju, dijalizu i transplantaciju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
PETAR KES ; Zavod za nefrologiju, arterijsku hipertenziju, dijalizu i transplantaciju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
NIKOLINA BAŠIĆ JUKIĆ ; Zavod za nefrologiju, arterijsku hipertenziju, dijalizu i transplantaciju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska

Sažetak

WNt 4 is a secreted glycoprotein that is critical for nephrogenesis during mesenchymal to epithelial transformation. Lately there are some experimental modles witch confirm a role of Wnt 4 during regeneration process in acute renal failure. on the other hand there are some evidence that Wnt 4 plays important role in renal fibrosis during experimental renal injury in rats that provide tubuloinerstitial fibrosis. When will Wnt 4 have a protective role or when will induce fibrosis still is not known and therefore futher studies will be necessary to gain a more precise understanding.

Ključne riječi

Wnt; kidney; tubulointerstitial fibrosis; acute renal failure

Hrčak ID:

99540

URI

https://hrcak.srce.hr/99540

Datum izdavanja:

3.4.2013.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.588 *