Izvorni znanstveni članak

Biocompatible Polymer Blends of Poly(D,L-lactic acid-co-glycolic acid) and Triblock PCL-PDMS-PCL Copolymers: Their Characterizations and Degradations

Alexandra Porjazoska ; TUBITAK-Marmara Research Center, Research Institute of Chemical Technologies and Materials, 41470 Gebze-Kocaeli, Turkey
Oksan Karal-Yilmaz ; TUBITAK-Marmara Research Center, Research Institute of Chemical Technologies and Materials, 41470 Gebze-Kocaeli, Turkey
Nilhan Kayaman-Apohan ; TUBITAK-Marmara Research Center, Research Institute of Chemical Technologies and Materials, 41470 Gebze-Kocaeli, Turkey
Maja Cvetkovska ; The »Sts. Cyril and Methodius« University, Faculty of Technology and Metallurgy, 1000 Skopje, Republic of Macedonia
Bahattin M. Baysal ; TUBITAK-Marmara Research Center, Research Institute of Chemical Technologies and Materials, 41470 Gebze-Kocaeli, Turkey

Sažetak

Polymer blends of poly(D,L-lactic-co-glycolic acid), PDLLGA, and triblock polycaprolactonepoly(dimethylsiloxane)-polycaprolactone (PCL-PDMS-PCL) copolymer, TEGOMER, were obtained by coprecipitation from their chloroform mixed solutions into methanol and were characterized by differential scanning calorimetry (DSC), Fourier transform infrared (FTIR), degradation tests and scanning electron microscopy (SEM). Binary blends of PDLLGA/TEGOMER were found to be partially miscible according to DSC measurements and FTIR analysis. Stressstrain results showed that addition of TEGOMER improved significantly the overall toughness of PDLLGA. Degradation of PDLLGA/TEGOMER blends was investigated in phosphate buffered saline at pH = 7.4 and 37 °C, and the morphology of the blends during degradation was examined by scanning electron microscopy.

Ključne riječi

poly(D,L-lactic acid-co-glycolic acid); polycaprolactone-poly(dimethylsiloxane)-polycaprolactone; degradation; blends

Hrčak ID:

102967

URI

https://hrcak.srce.hr/102967

Datum izdavanja:

30.11.2004.

Posjeta: 2.130 *