Izvorni znanstveni članak
Pharmacological effect and clinical application of aminofluorides (Elmex)
Ileana Linčir
; Katedra za farmakologiju Stomatološkog fakulteta, Zagreb
Sažetak
The value of local application of fluorides in the prevention of caries of the teeth has been generally recognized. They contribute considerably to the reduction of incidence and rate of progression of caries, particularly when added to drinking water. In the reaction, which begins promptly, the most important role is played by the surface activity: of aminofluorides. On the ename! surface a protective layer of calcium fluoride is made, while in the enamel hydroxilapatite is substituted with fluorapatite. In addition to the effect on the inorganic part of the enamel, aminofluorides act also bacteriostatically on streptococci in the dental plaque and inhibit the enzymatic processes during which bacteria cause glycolysis and production of acids. Clinical investigations have shown the reduction of caries from 27— 40% by the application of am inofluorides. Besides, desensitization of sensitive dentin has been also achieved. The indications for the use of aminofluorides are the following: prophylaxis of dental decay in children and in adults with highly active caries, high sensitivity of dentin and demineralization of the enamel under mobile prosthesis and orthodontic appliances.
Ključne riječi
Hrčak ID:
105834
URI
Datum izdavanja:
15.6.1979.
Posjeta: 2.982 *