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Post-vaccine glomerulonephritis in an infant with hereditary C2 complement deficiency: case study

Tanja Kersnik Levart ; Department of Pediatric Nephrology, University Medical Centre, Ljubljana, Slovenia

Puni tekst: engleski pdf 87 Kb

str. 569-573

preuzimanja: 699



Abstract We describe a case of a post vaccine immune
complex-mediated glomerulonephritis in an infant with
compound heterozygous mutations of C2 complement
component gene, which is the first such case in the literature.
The three and a half months old boy presented with
clinical and laboratory signs of nephritic syndrome and
was successfully treated with methylprednisolone. An explanation
of such a clinical picture may lie in the interaction
between C2 deficiency and vaccination.

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