Izvorni znanstveni članak
Influence of Allergy and Bacterial Colonization on the Quality of Life in Nasal Polyposis Patients
Hrvoje Mihalj
; University »Josip Juray Strossmayer«, University Hospital Centre Osijek, Department of Otorhinolaryngology and Head and Neck Surgery, Osijek, Croatia
Mirela Baus Lončar
; Institute »Ru|er Bo{kovi}«, Department of Molecular medicine, Zagreb, Croatia
Martina Mihalj
; University »Josip Juray Strossmayer«, School of Medicine, Department of Physiology and Immunology, Osijek, Croatia
Željko Zubčić
; University »Josip Juray Strossmayer«, University Hospital Centre Osijek, Department of Otorhinolaryngology and Head and Neck Surgery, Osijek, Croatia
Andrijana Včeva
; University »Josip Juray Strossmayer«, University Hospital Centre Osijek, Department of Otorhinolaryngology and Head and Neck Surgery, Osijek, Croatia
Maro Bujak
; Institute »Ruđer Bošković«, Department of Molecular medicine, Zagreb, Croatia
Josip Maleš
; University »Josip Juray Strossmayer«, University Hospital Centre Osijek, Department of Otorhinolaryngology and Head and Neck Surgery, Osijek, Croatia
Anđela Marić
; University »Josip Juray Strossmayer«, School of Medicine, Department of Anatomy and neuroscience, Osijek, Croatia
Sažetak
Allergies and bacterial colonization are frequently found in patients with chronic rhinosinuitis with nasal polyposis (CRSwNP). The aim of this study was to identify patients with allergy and present microorganisms in ethmoid sinus among the patients with refractory CRSwNP undergoing surgical treatment at the University Hospital Centre Osijek, and to compare their life quality, defined by SNOT-20 analysis (sinonasal outcome test) to the rest of patients, and a con- trol group consisting of patients undergoing septoplasty but free of allergy and/or CRS. An additional aim was to iden- tify specific types and strains of microorganisms (bacteria and fungi) found in these patients, in order to compare them to other reports, and to revise the empirical antimicrobial therapy. In this paper we demonstrate a high incidence of bacte- rial colonization (83.3%) among CRSwNP patients. As in previous studies, gram positive aerobes were the most fre- quently isolated bacteria and all of them were covered by specific antibiotics given before the specimen collection. Allergy was found in only 20% of these patients, who presented with a reduced quality of life when compared to the control group and CRSwNP without allergy. Significantly more frequent dominant symptoms in these patients were cough, frustration and irritation. In the line with this finding is the objective assessment by endoscopy (Malm score) that showed more prominent nasal polyposis in allergy patients.
Ključne riječi
chronic rhinosinuitis; nasal polyposis; allergy; bacterial colonization
Hrčak ID:
118354
URI
Datum izdavanja:
30.12.2013.
Posjeta: 1.685 *