Paediatria Croatica, Vol. 57 No. 3, 2013.
Stručni rad
C3 glomerulonephritis: two pediatric cases
Meral Torun Bayram
; Department of Pediatrics, Dokuz Eylul University, School of Medicine, Izmir, Turkey
Demet Alaygut
; Department of Pediatrics, Dokuz Eylul University, School of Medicine, Izmir, Turkey
Sulen Sarioglu
; Department of Pathology, Dokuz Eylul University, School of Medicine, Izmir, Turkey
Alper Soylu
; Department of Pediatrics, Dokuz Eylul University, School of Medicine, Izmir, Turkey
Mehmet Turkmen
; Department of Pediatrics, Dokuz Eylul University, School of Medicine, Izmir, Turkey
Salih Kavukcu
; Department of Pediatrics, Dokuz Eylul University, School of Medicine, Izmir, Turkey
Sažetak
C3 glomerulopathy defi nes a group of diseases characterized with deposition of C3 alone in the glomeruli in the absence of deposition
of immunoglobulin or other complement products. These diseases include dense deposit disease, type 1 membranoproliferative
glomerulonephritis (MPGN), familial type 3 MPGN, familial C3 glomerulonephritis associated with mutation in complement
factor H related protein 5 and idiopathic C3 glomerulonephritis. Recently, dysregulation of the complement system has been
accused in the disease pathogenesis. In this manuscript, two pediatric cases of probable C3 glomerulonephritis according to clinical
and renal biopsy fi ndings are presented. One of the cases had presented with the nephrotic-nephritic syndrome and the other with
macroscopic hematuria, and both had good prognosis.
Ključne riječi
glomerulonephritis, membranous; immunoglobulins; infant; child
Hrčak ID:
119757
URI
Datum izdavanja:
30.9.2013.
Posjeta: 855 *