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A Case of Superficial Granulomatous Pyoderma Mimicking a Basal Cell Carcinoma

Paolo Rosina ; University of Verona
Anastasia Papagrigoraki ; University of Verona
Chiara Colato ; University of Verona


Puni tekst: engleski PDF 208 Kb

str. 48-48

preuzimanja: 919

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Sažetak

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis of unknown etiology with distinct clinical manifestations, frequently associated with systemic diseases. Four clinical and histological variants have been described: ulcerative, pustular, bullous and vegetative. We report a case of Superficial Granulomatous Pyoderma (SGP), a vegetative form of PG, in a 40-year-old woman. Physical examination revealed an erythematous crusted plaque, measuring 2 cm in diameter, located on her left hip, presented 18 months ago. Dermoscopy showed lack of pigment network, large gray-blue ovoid nests, irregular peripheral vessels and ulceration. Laboratory examinations were normal; smears and cultures for bacteria and fungi were negative. Clinical and dermatoscopical presentation suggested diagnosis of a basal cell carcinoma. The lesion had been totally removed: histological examination showed pseudoepitheliomatous hyperplasia with intraepidermal micro-abscesses and prominent dermal inflammatory infiltrate with typical three-layered granulomas consisting of palisading suppurative granulomas surrounded by plasma cell and eosinophils (diffuse neutrophilic infiltration with dermal inflammatory infiltrates consisting of epithelioid histiocytes, lymphocytes and multinucleated giant cells). Based on clinical and histological correlation, SPG was definitively diagnosed.

Ključne riječi

superficial granulomatous pyoderma; pyoderma gangrenosum; dermoscopy

Hrčak ID:

121309

URI

https://hrcak.srce.hr/121309

Datum izdavanja:

15.5.2014.

Posjeta: 1.637 *