Original scientific paper

https://doi.org/10.5562/cca2087

Indium(III) Trifluoromethanesulfonate: a Reusable Catalyst for the Sol-vent-free Synthesis of some Quinazolinones/thiones

Bahador Karami ; Department of Chemistry, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
Saeed Khodabakhshi ; Young Researchers and Elite Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran
Sajad Karami ; Department of Chemistry, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran

Abstract

An environmentally friendly and clean procedure gives octahydroquinazolinones/thiones by a simple Bigi-nelli condensation of urea/thiourea, aromatic aldehydes, and cyclic 1,3-diones in the presence of indi-um(III) trifluoromethanesulfonate (In(OTf)3) in solventless conditions. This method has advantages such as avoidance of the organic solvents, high yield of pure products without any by-product, short reaction times and operational simplicity.(doi: 10.5562/cca2087)

Keywords

octahydroquinazolinones/thiones; indium (III) trifluoromethanesulfonate; urea/thiourea; aldehyde

Hrčak ID:

122276

URI

https://hrcak.srce.hr/122276

Publication date:

30.4.2014.

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