Medica Jadertina, Vol. 44 No. 1-2, 2014.
Stručni rad
The value of contact endoscopy in the screening of precancerous lesions of laryngeal epithelium in smokers
Marisa Klančnik
; KBC Split, Klinika za bolesti uha, grla i nosa s kirurgijom glave i vrata
Zaviša Čolović
; KBC Split, Klinika za bolesti uha, grla i nosa s kirurgijom glave i vrata
Nikola Kolja Poljak
; KBC Split, Klinika za bolesti uha, grla i nosa s kirurgijom glave i vrata
Draško Cikojević
; KBC Split, Klinika za bolesti uha, grla i nosa s kirurgijom glave i vrata
Mirko Kontić
; KBC Split, Klinika za bolesti uha, grla i nosa s kirurgijom glave i vrata
Jadranka Vela Ljubić
; KBC Split, Klinika za bolesti uha, grla i nosa s kirurgijom glave i vrata
Sažetak
Contact endoscopy as a noninvasive diagnostic method provides an insight into the microscopic picture of laryngeal mucosa epithelium. The cells are analyzed in vivo, thus obviating the possible cell damage and distortion on preparation. In the present study, vocal cord mucosa epithelium was analyzed by contact endoscopy in subjects still free from clinical symptoms of disease. Initial laryngeal lesions are macroscopically invisible, and early detection of these changes is associated with better prognosis and easier management. The present study also demonstrated a considerably higher prevalence of initial pathologic lesions of the larynx in smokers versus nonsmokers. This method is also suitable for patients with chronic laryngitis or pronounced leukoplakia to identify the best site of biopsy for histopathologic analysis, as it offers a more reliable diagnosis with less damage to laryngeal mucosa.
This noninvasive method should preferably be also used in smokers with voice alteration because it provides a microscopic insight into initial pathologic lesions of the vocal cord mucosa epithelium.
Ključne riječi
contact endoscopy, larynx; precancerous lesion; smoke
Hrčak ID:
122385
URI
Datum izdavanja:
2.6.2014.
Posjeta: 2.411 *