Izvorni znanstveni članak

Relationship between vitamin D status and bone mineral density in Croatian postmenopausal women

Nadica Laktašić-Žerjavić ; Klinika za reumatske bolesti i rehabilitaciju, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Krešimir Rukavina ; Medicinski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Đurđica Babić-Naglić ; Klinika za reumatske bolesti i rehabilitaciju, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Božidar Ćurković ; Klinika za reumatske bolesti i rehabilitaciju, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Branimir Anić ; Zavod za kliničku imunologiju i reumatologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Dragica Soldo-Jureša ; Sveučilišna klinika za dijabetes, endokrinologiju i bolesti metabolizma “Vuk Vrhovac”, Klinička bolnica “Merkur”, Zagreb, Hrvatska

Sažetak

The aim of the study was to investigate correlation of vitamin D status meassured as 25-hydoxyvitamin D (25(OH)D) concentration with bone mineral density (BMD) in Croatian postmenopausal women. This study was based on the sample of 194 adult, postmenopausal women aged 50 years or over from Croatia. Assessment of 25(OH)D concentration and BMD by dual-energy x-ray absorptiometry (DXA) was performed to all participants. The average age of the participants in this study was 60.6 years. The average menopause duration was 11.4 years. Among the included participants only 13.9 % of women complied with diagnostic criteria for osteoporosis. Mean serum concentration of 25(OH)D was 49.1 nmol/L (±17.1 SD). The prevalence of severe vitamin D deficiency was significantly higher in participants with osteoporosis compared with participants with normal BMD (<30 nmol/L; 29.6 % vs. 9.8 %). Correlation between serum 25(OH)D concentration and BMD was significant and positive at the proximal femur (r=0.18; p=0.026), and at the femoral neck (r=0.15; p<0.001). The results of this study indicate significant and positive correlation between serum 25(OH)D concentration and BMD meassured at the proximal femur and at the femoral neck in Croatian postmenopausal women.

Ključne riječi

bone density, mineral; calcifediol, 25-hydroxyvitamin D3; osteoporosis, postmenopausal

Hrčak ID:

123591

URI

https://hrcak.srce.hr/123591

Datum izdavanja:

1.6.2013.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.431 *