Stručni rad

Pathology diagnosis of idiopathic inflammatory myopathies

Leo Pažanin ; Klinički zavod za patologiju “Ljudevit Jurak”, Klinički bolnički centar “Sestre milosrdnice”, Zagreb, Hrvatska

Sažetak

The idiopathic inflammatory myopathies represent a group of immunologically mediated diseases characterized by inflammation of skeletal muscle potentially leading to irreversible damage. On the basis of clinical, histological and immunological features dermatomyositis, polymyositis and sporadic inclusion-body myositis are recognized as separate entities. A definitive diagnosis of idiopathic inflammatory myopathies requires detailed histological, histochemical, immunohistochemical and electron-microscopic analysis of adequate muscle biopsy sample. However, in spite of thorough morphological analysis distinction of these disorders is not always straightforward and a close clinicopathological correlation is often essential to reach a correct diagnosis. Detailed morphological features of idiopathic inflammatory myopathies and their relationship to pathogenesis is outlined.

Ključne riječi

myositis; inflammatory myopathy; pathology diagnosis

Hrčak ID:

124038

URI

https://hrcak.srce.hr/124038

Datum izdavanja:

25.10.2012.

Podaci na drugim jezicima: hrvatski

Posjeta: 5.301 *