Stručni rad

Treatment of systemic lupus erythematosus

Dijana Perković ; Odsjek za kliničku imunologiju i reumatologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Split, Split, Hrvatska
Dušanka Martinović Kaliterna ; Odsjek za kliničku imunologiju i reumatologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Split, Split, Hrvatska
Daniela Marasović Krstulović ; Odsjek za kliničku imunologiju i reumatologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Split, Split, Hrvatska

Sažetak

Treatment of systemic lupus erythematosus is very difficult because of heterogeneous clinical manifestations. Standard therapy includes non-steroidal anti-inflammatory drugs, glucocorticoids, antimalarials and cytotoxic agents. A numerous biological agents have been investigated for treatment of the systemic lupus erythematosus. They are directed to B and T cell depletion, blockade of co-stimulatory molecules, inhibition of cytokines and complement modulation. Sirolimus, tacrolimus, autologous hematopoietic stem cell transplantation and allogenic mesenchymal stem cells transplantation have been also investigated for treatment of systemic lupus erythematosus.

Ključne riječi

systemic lupus erythematosus; treatment; glucocorticoids; cytotoxic agents; biological agents

Hrčak ID:

124382

URI

https://hrcak.srce.hr/124382

Datum izdavanja:

1.4.2012.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.135 *