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Early rheumatoid arthritis

Đurđica Babić-Naglić ; Klinika za reumatske bolesti i rehabilitaciju, Klinički bolnički centar Zagreb, Zagreb, Hrvatska


Puni tekst: hrvatski pdf 458 Kb

str. 26-33

preuzimanja: 4.760

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Sažetak

Rheumatoid arthritis (RA) is chronic joint disease which if untreated leads to permanent structural damage and disability. Early diagnosis and therapy are the main requests for good clinical practice. Early diagnosis tools include specific clinical assesment, serological, immunogenetic and radiological evaluation. Disease activity score is cornerstone in clinical assesment, rheumatoid factor and anti-cyclic citrullinated peptide antibodies (anti-CCP) are very specific serological parameters. The shared epitope containing HLA-DRB1* alleles represent the most significant genetic risk for RA. Magnetic resonance and ultrasound imaging are very sensitive methods in early phase of disease.

Ključne riječi

rheumatoid arthritis; early diagnosis; anti-CCP; HLA-DRB1

Hrčak ID:

125241

URI

https://hrcak.srce.hr/125241

Datum izdavanja:

17.10.2008.

Podaci na drugim jezicima: hrvatski

Posjeta: 6.283 *