Reumatizam, Vol. 55 No. 2, 2008.
Izlaganje sa skupa
Strontium ranelate’s (Osseor®) dual mode of action: increasing bone mass and decreasing bone resorption
Dušanka Martinović Kaliterna
; Odsjek za kliničku imunologiju i reumatologiju, Klinika za unutarnje bolesti, Klinički bolnički centar Split, Split, Hrvatska
Sažetak
Strontium ranelate has unique dual mode of action on bone remodeling through increased bone formation and decreased bone resorption. As a consequence, there is increased bone mass and bone strength, leading to reduced number of vertebral and nonvertebral fractures. Although strontium bone distribution is heterogeneous, higher concentrations of strontium are found in younger bones. Long term treatment with strontium ranelate does not lead to any change in bone mineral distribution, mineral composition or crystal stability, nor is strontium accumulated in bone.
Ključne riječi
strontium ranelate; bone mass; bone resorption; minerals
Hrčak ID:
125251
URI
Datum izdavanja:
17.10.2008.
Posjeta: 699 *