Reumatizam, Vol. 54 No. 1, 2007.
Stručni rad
Proposal for anti-TNFα therapy in adult patients with rheumatoid arthritis
Božidar Ćurković
; Hrvatsko reumatološko društvo HLZ-a, Zagreb, Hrvatska
Đurđica Babić-Naglić
; Hrvatsko reumatološko društvo HLZ-a, Zagreb, Hrvatska
Jadranka Morović-Vergles
; Hrvatsko reumatološko društvo HLZ-a, Zagreb, Hrvatska
Branimir Anić
; Hrvatsko reumatološko društvo HLZ-a, Zagreb, Hrvatska
Simeon Grazio
; Hrvatsko reumatološko društvo HLZ-a, Zagreb, Hrvatska
Sažetak
Rheumatoid arthritis is a chronic, inflammatory disease with the prevalence about 1%. Rheumatoid arthritis is characterized with synovitis, erosive changes of the joints, pain and functional deficit. Etiology of the disease is unknown. In the pathogenesis of rheumatoid arthritis the key role have proinflammatory citokines, particularly, tumour necrosis factor (TNFα). TNFα blockers have documented, fast and continuous efficacy with generaly well accepted safety profile. Nowadays, TNFα antagonists are established drugs in early and late phase of rheumatoid arthritis. Prescription of TNFα antagonists is controlled, according local restrictions, regarding high costs of the therapy. On behalf of the Croatian Society for Rheumatology we propose recommendations for the TNFα antagonist therapy in rheumatoid arthritis.
Ključne riječi
rheumatoid arthritis; TNF inhibitors; recommendations
Hrčak ID:
125391
URI
Datum izdavanja:
1.7.2007.
Posjeta: 922 *