Reumatizam, Vol. 53 No. 1, 2006.
Pregledni rad
HLA-B27 gene: polymorphism, evolution, distribution, and association with spondyloartopathies
Zorana Grubić
; Zavod za tipizaciju tkiva, Klinika za urologiju, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
Sažetak
The association between HLA-B27 and ankylosing spondylitis is well established more than thirty years. In spite of numerous studies in this field, a lot of unknown is still present. In this review, polymorphism, evolution, distribution and current pathogenetic hypotheses are presented.
Ključne riječi
HLA-B27; polymorphism; evolution; ankylosing spondylitis; spondyloarthropathies; population study
Hrčak ID:
125881
URI
Datum izdavanja:
1.7.2006.
Posjeta: 2.892 *