Pismo uredniku

Gorlin-Goltz Syndrome and Stroke: a Case report

Hrvoje Budinčević ; Stroke and Intensive Care Unit. Department of neurology, University Hospital „Sveti Duh“
Katarina Starčević
Ivan Bielen
Vida Demarin

Sažetak

We report on the case of a 32-years old male patient who was previously diagnosed with Gorlin-Goltz syndrome. The patient presented with sudden-onset right-sided hemiparesis, supranuclear facioparesis, and motor aphasia. He was treated with thrombolytic therapy, which successfully alleviated the symptoms. Subsequent radiologic work-up revealed anomalies in the vertebral arteries, a bifid rib, an ischemic lesion in the supply area of the left middle cerebral artery, and falx calcifications. Laboratory tests showed a 4G/4G polymorphism of the plasminogen activator inhibitor 1  (PAI-1) gene whose correlation with stroke is discussed in the article.

Ključne riječi

Gorlin-Goltz syndrome; stroke; PAI-1 gene polymorphism

Hrčak ID:

126596

URI

https://hrcak.srce.hr/126596

Datum izdavanja:

10.9.2014.

Posjeta: 1.035 *