Izvorni znanstveni članak
https://doi.org/10.3325/cmj.2014.55.337
Cerebrospinal fluid physiology: visualization of cerebrospinal fluid dynamics using the magnetic resonance imaging Time-Spatial Inversion Pulse method
Shinya Yamada
orcid.org/0000-0002-2657-3494
; Division of Neurosurgery, ToshibaRinkan Hospital, Kanagawa, Japan
Sažetak
Previously there have been no methods for directly tracing
the flow of cerebrospinal fluid (CSF) under physiological
conditions, and the circulation of CSF has therefore been
studied and visualized by injecting a radioactively labeled
tracer or contrast medium visible in x-ray images. The
newly developed Time-Spatial Inversion Pulse (Time-SLIP)
method makes it possible to directly visualize the flow of
CSF using magnetic resonance imaging (MRI), permitting
CSF dynamics to be depicted in a certain time frame. The
CSF dynamics visualized using Time-SLIP has been found
to differ markedly from the classical CSF circulation theory
described in medical textbooks. It can be said that research
on CSF dynamics has advanced to the next stage
with the use of this innovative imaging method. Obtaining
a more accurate understanding of normal CSF physiology
and pathophysiology should lead to improved diagnostic
accuracy, permit the identification of new etiological factors
in a variety of diseases, and promote the development
of new therapeutic approaches.
Ključne riječi
Hrčak ID:
129940
URI
Datum izdavanja:
15.8.2014.
Posjeta: 1.899 *