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Oxidative stress, hematobiochemical parameters, trace elements and vitamins in dogs with zinc responsive dermatosis.

Shafayat A. Beigh ; Division of Veterinary Medicine, Faculty of Veterinary Science and Animal Husbandry, Shere-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Alasteng- Jammu, India
Jaswinder S. Soodan ; Department of Teaching Veterinary Clinical Complex, Faculty of Veterinary Science and Animal Husbandry, Shere-e-Kashmir University of Agricultural Sciences and Technology of Jammu R. S. Pura Jammu ( J& K), India
Salik Nazki ; Division of Veterinary Microbiology and Immunology, Faculty of Veterinary Science and Animal Husbandary, Shere-e-Kashmir University of Agricultural Sciences and Technology of Kahmir, Shuhama, Alasteng (J & K), India
Adil M. Khan ; Department of Veterinary Pharmacology and Toxicology, Guru Angad Dev Veterinary and Animal Science University, Ludhiana, Punjab, India


Puni tekst: engleski pdf 174 Kb

str. 591-600

preuzimanja: 467

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Sažetak

The aim of this study was to examine the hemato-biochemical alterations and evaluate the oxidative stress indices in the blood of dogs with zinc responsive dermatosis. The study included 9 dogs with clinically established diagnosis of zinc responsive dermatosis and 6 dogs as a healthy control. The clinical disease was characterized by alopecia, erythema, hyperkeratotic foot pads and scaling around the eyes, chin, eyes, head and legs. The MDA levels were significantly (P<0.01) higher, whereas superoxide dismutase and catalase activity were significantly (P<0.01) lower when compared to healthy control dogs. Hematology revealed significant neutrophilia and lymphopenia, along with anemia. Biochemical examination revealed a significant (P<0.05) decrease in albumin, A:G ratio and glucose levels, and a significant increase (P<0.05) in globulin level. Plasma zinc, vitamin A and C were significantly decreased, however copper levels were increased. In conclusion, zinc responsive dermatosis is accompanied by oxidative stress and anemia, and affected animals are susceptible to infection.

Ključne riječi

biochemical, dermatitis, hematology, hyperkeratotic, oxidative stress, zinc

Hrčak ID:

130369

URI

https://hrcak.srce.hr/130369

Podaci na drugim jezicima: hrvatski

Posjeta: 932 *