Pregledni rad

Infectious gangrene as a clinical entity

Tomislav Bruketa ; Zavod za gastrointestinalnu kirurgiju, Klinika za kirurgiju, KBC Zagreb, Zagreb, Hrvatska
Ivan Puljiz ; Klinika za infektivne bolesti "Dr. Fran Mihaljević", Zagreb, Hrvatska

Sažetak

Infectious gangrenes or necrotizing soft tissue infections are severe subcutaneous tissue infections with high mortality rates. Infections are often preceded by a surgical procedure or trauma. There are many classifications of infectious gangrenes, however the most commonly used in practice is microbiological classification into type I (polymicrobial) and type II (caused by Streptococcus). The clinical presentation of infectious gangrene includes intense pain in the wound area, crepitations, secretion, the occurrence of bullae and rapid development of septic shock. The external appearance of the wound often does not correlate with the actual condition and may be the reason for late diagnosis. The diagnosis of the disease is based on clinical features, laboratory findings, radiological examinations, microbiological results, and is confirmed by surgical exploration of the affected area which is also a therapeutic procedure. Gas formation in the soft tissues is a typical sign of necrotizing infections and indicates the beginning of treatment. Lack of timely and aggressive treatment usually leads to poor disease outcome. Optimal treatment consists of prompt and extensive surgical wound exploration and necrotic tissue removal, combined antibiotic therapy and necessary symptomatic and supportive therapy.

Ključne riječi

Infectious gangrene; surgical treatment; antibiotic therapy

Hrčak ID:

133453

URI

https://hrcak.srce.hr/133453

Datum izdavanja:

31.3.2014.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.666 *