Infektološki glasnik, Vol. 27 No. 1, 2007.
Pregledni rad
Molecular detection and genetic characterization of mumps virus
T. Košutić Gulija
M. Šantak
R. Mažuran
M. Baričević
J. Ivančić-Jelečki
R. Jug
D. Forčić
Sažetak
Mumps is an RNA virus that is a cause of the vaccine preventable disease, mumps. In clinical specimens and supernatants of the infected cell cultures its RNA is detectable by RT-PCR test. Advantages of RT-PCR are rapidity, specificity and sensitivity. Genetic characterization and genotyping are basis for molecular epidemiological surveillance of the wild type mumps virus. Mumps outbreaks are also detected in a highly vaccinated population. Molecular detection and characterization of wild and vaccine types of mumps virus has been performed in Croatia since the late nineties.
Ključne riječi
Molecular detection; genotyping; molecular epidemiology
Hrčak ID:
12636
URI
Datum izdavanja:
23.3.2007.
Posjeta: 3.619 *