Izvorni znanstveni članak
https://doi.org/10.15644/asc49/1/2
Periodontal Disease and its Association with Angiographically Verified Coronary Artery Disease
Domagoj Vražić
; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu, Hrvatska; Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Hrvatska
Zoran Miovski
; Klinika za bolesti srca i krvnih žila Kliničkog bolničkog centra Zagreb, Hrvatska
Maja Strozzi
; Klinika za bolesti srca i krvnih žila Kliničkog bolničkog centra Zagreb, Hrvatska
Ivan Puhar
; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu, Hrvatska; Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Hrvatska
Ana Badovinac
; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu, Hrvatska; Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Hrvatska
Darko Božić
; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu, Hrvatska; Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Hrvatska
Darije Plančak
; Zavod za parodontologiju Stomatološkog fakulteta Sveučilišta u Zagrebu, Hrvatska; Klinički zavod za parodontologiju Kliničkog bolničkog centra Zagreb, Hrvatska
Sažetak
Purpose: The aim of this research was to investigate the association of chronic and aggressive
periodontitis with the severity of coronary artery disease which was angiographically verified.
Material and methods: Subjects were selected among the hospitalized patients at the University
Hospital Centre Zagreb who had coronary angiography done because of the chest pain. Thorough
clinical examination included periodontal indices and clinical and socio-demographic characteristics
of participants. Subjects were divided in two test groups, acute coronary syndrome (ACS) and
stable coronary artery disease (CAD), and the control group with no significant CAD. Data were
analyzed using Kruskal-Wallis and Pearson’s Chi-Square test. Results: From 106 subjects, 66
(62.3%) were hospitalized for ACS, 22 (20.7%) had stable CAD and only 18 (17.0%) had no significant
CAD. Only 26 (24.5%) out of 106 patients were never smokers (p<0.05). Chronic periodontitis
was the most common finding with 68.2% in ACS group and 54.5% in stable CAD group, while
healthy patients without periodontitis (72.6%) were dominant in the control group (p<0.001).
Stable CAD group had the highest mean probing depth (PD) 3.92±1.16, gingival recession (GR)
1.34±0.78, clinical attachment level (CAL) 4.60±1.41 and bleeding on probing (BOP) 45.98±26.19
values, whereas ACS group had mean PD value of 3.77±0.91, GR 1.11±0.66, CAL 4.32±1.08 and
BOP 41.30±22.09, and no significant CAD group had mean PD value of 3.27±0.97, GR 0.69±0.37,
CAL 3.62±1.04 and BOP 26.39±13.92 (p<0.05). Conclusion: Periodontitis was shown to be associated
with angiographically verified coronary artery disease. Physical inactivity, poor oral hygiene
and periodontal inflammation were observed in patients with ACS and stable CAD.
Ključne riječi
Periodontitis; Periodontal Index; Cardiovascular Diseases; Coronary Artery Disease; Coronary Angiography
Hrčak ID:
136813
URI
Datum izdavanja:
24.3.2015.
Posjeta: 4.176 *