Periodicum biologorum, Vol. 117 No. 1, 2015.
Original scientific paper
Non-pharmacological treatment of osteoporosis with Nuclear Magnetic Resonance Therapy (NMR-Therapy)
DALIBOR KRPAN
; Poliklinika K-CENTAR, Zagreb, Croatia
BARBARA STRITZINGER
; Ludwig Boltzmann Cluster for Rheumatology, Balneology and Rehabilitation, Department for Rehabilitation, Saalfelden, Austria
IVAN LUKENDA LUKENDA
; Poliklinika K-CENTAR, Zagreb, Croatia
JOAKIM OVERBECK
; 1_Private Consultant Surgeon, Deggendorf, Germany;2_Poliklinika K-CENTAR, Zagreb, Croatia
WERNER KULLICH
; Ludwig Boltzmann Department for Rehabilitation Thorerstrasse 26, 5760 Saalfelden, Austria
Abstract
Objectives: To demonstrate the long-term effects of the therapeutic use of nuclear magnetic resonance (NMR) on bone mineral density (BMD)
parameters in patients with osteoporosis.
Methods: We enrolled 103 patients aged between 45 and 89 years who
had osteoporosis with a T-score of bone mineral density less than -2.5. All
patients received an osteoporosis treatment with low field nuclear magnetic resonance using a special NMR device (MBST, MedTec, Germany) for one hour per day on 10 consecutive days. At baseline and 12 months after NMR treatment the BMD was measured by DEXA. Additionally, the levels of the bone turnover markers osteocalcin and bone crosslaps (B-CTX; crosslinked telopeptides of collagen 1) were measured by immunoassays.
Results: BMD and serum levels of osteocalcin increased significantly
from baseline to 12 months. B-CTX remained stable.
Conclusions: Under therapeutically use of NMR-Therapy, BMD-parameters
increased during 12 months after a treatment block (10 x 1h).
Therefore, NMR-Therapy can be considered a useful alternative or supplement to medical therapy in patients with osteoporosis.
Keywords
Nuclear magnetic resonance therapy; osteoporosis; bone mineral density; BMD; DXA; osteocalcin; crosslaps
Hrčak ID:
139535
URI
Publication date:
31.3.2015.
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