Izvorni znanstveni članak
Serum levels of nitric oxide as a predictor of survival in acute respiratory distress syndrome caused by H1N1 pneumonia?
Pedja Kovačević
orcid.org/0000-0001-6654-5351
; Department for Physiology, Medical School Banja Luka, Bosnia - Herzegovina; Medical Intensive Care Unit Clinical Centre Banja Luka Filipa Kljajića Fiće 49. Banja Luka 78000 Republika Srpska, BiH
Zvezdana Rajkovača
; Department for Physiology, Medical School Banja Luka, Bosnia - Herzegovina
Saša Dragić
; Medical Intensive Care Unit, Clinical Centre Banja Luka, Bosnia-Herzegovina
Jadranka Vidović
; Medical Intensive Care Unit, Clinical Centre Banja Luka, Bosnia-Herzegovina
Slavica Zeljković
; Medical Intensive Care Unit, Clinical Centre Banja Luka, Bosnia-Herzegovina
Danica Momčičević
; Medical Intensive Care Unit, Clinical Centre Banja Luka, Bosnia-Herzegovina
Tijana Kovačević
; Department for Hospital Pharmacy, Clinical Centre Banja Luka, Bosnia-Herzegovina
Sažetak
A large number of studies show elevated levels of nitric oxide (NO) in infective syndromes, but there is an insufficient number of studies which have investigated serum levels of NO in patients with acute respiratory distress syndrome (ARDS), especially in relation to survival. Hence, we created a study with the aim of determining the NO levels in relation to ARDS survival.
Serum levels of NO were measured by Griess reaction in 29 patients [16 men (55%), mean age years 52.72±18]. All data were statistically analyzed using one way ANOVA.
Our results show significantly higher serum NO levels in ARDS survivors compared to ARDS non-survivors, (p < 0.05). We conclude that higher serum levels of NO are strongly associated with better clinical outcomes, including increased survival.
Ključne riječi
acute respiratory distress syndrome; nitrogen oxide species; outcome
Hrčak ID:
140719
URI
Datum izdavanja:
1.4.2015.
Posjeta: 915 *