Infektološki glasnik, Vol. 34 No. 4, 2014.
Izvorni znanstveni članak
Mycoplasma genitalium – sexually transmitted pathogen that cannot be ignored
Sunčanica Ljubin Sternak
; Nastavni zavod za javno zdravstvo "Dr. Andrija Štampar", Zagreb, Hrvatska
Tatjana Marijan
; Nastavni zavod za javno zdravstvo "Dr. Andrija Štampar", Zagreb, Hrvatska
Jasmina Vraneš
; Nastavni zavod za javno zdravstvo "Dr. Andrija Štampar", Zagreb, Hrvatska
Sažetak
The development of molecular methods has enabled efficient diagnosis of infections caused by Mycoplasma genitalium (M. genitalium). However, data on M. genitalium infection in Croatia are scarce due to the complexity of detection method for this bacterium which is still not routinely used in clinical laboratories. The aim of this study was to determine the prevalence of M. genitalium in cervical swabs and male urethral swabs referred for C. trachomatis diagnostics to the Clinical Microbiology Department of the Teaching Institute for Public Health "Dr. Andrija Štampar". The study was conducted over a period of seven months. From a total of 5057 received cervical swabs that were tested for C. trachomatis, 195 samples were tested for M. genitalium (99 positive and 96 negative for C. trachomatis). Additionally, 52 urethral swabs collected from men with nongonococcal urethritis were tested for M. genitalium (18 positive and 34 negative for C. trachomatis). Both, C. trachomatis and M. genitalium were detected using realtime PCR methods, while gonococcal infection was excluded by direct microscopy. The incidence of C. trachomatis infection in cervical swabs was 2.04% (103/5057). Out of 195 cervical swabs tested M. genitalium was proved in six samples (3.08%). All samples found positive for M. genitalium were positive for C. trachomatis as well (6/99), while not a single C. trachomatis negative sample was positive for M. genitalium (0/96; P < 0.05). In the urethral swabs of men with NGU, M. genitalium was detected in one sample that was C. trachomatis negative. M. genitalium is important, but in our midst under-recognized and under-diagnosed sexually transmitted pathogen. Based on the results of the study, testing for M. genitalium should become an integral part of routine protocol for diagnosis of sexually transmitted diseases in women with C. trachomatis infection.
Ključne riječi
Mycoplasma genitalium; microbiological diagnostics; sexually transmitted diseases; prevalence
Hrčak ID:
143358
URI
Datum izdavanja:
30.12.2014.
Posjeta: 2.447 *