Acta clinica Croatica, Vol. 44 No. 4, 2005.
Ostalo
Transsphenoidal Encephalocele - Case Report
Andreja Vidačić
Martina Matovinović
Andreja Marić
Davorka Herman
Jure Murgić
Hrvoje Ivan Pećina
Vatroslav Čerina
Milan Vrkljan
Sažetak
A case of a 32-year-old woman with transsphenoidal encephalocele is presented. Encephaloceles are congenital defects in the skull through which meninges and brain tissues herniate. Basal encephaloceles account for 1.5% of all encephaloceles and are found in 1:35,000 live births. Transsphenoidal basal encephaloceles are very rare, accounting for only 5% of all basal encephaloceles. The pituitary and surrounding structures are drawn into the encephalocele with visual and hormonal disturbances. Transsphenoidal encephalocele rarely occurs in adult patients. Our patient presented with right-sided headaches, episodes of impaired vision on the right eye, a feeling of oozing down the pharynx, and secondary amenorrhea. In childhood, she had been diagnosed with pituitary somatic retardation and treated by pediatrician with thyroid replacement therapy from age 5 to 8. Due to strong headache and suspicion of a pathologic disorder in the sellar region, MRI was performed to demonstrate a transsphenoidal encephalocele, sella structures placed in the right nasopharynx and chiasm of the optic nerve that was shifted caudally. Endocrinologic analysis revealed low levels of gonadotropins, antidiuretic hormone and insulin-like growth factor 1, with a decreased level of growth hormone.
Ključne riječi
Encephalocele - diagnosis; Encephalocele - complications; Growth hormone - secretion; Headache - etiology; Case report
Hrčak ID:
14301
URI
Datum izdavanja:
1.12.2005.
Posjeta: 2.037 *