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Multiple Endocrine Neoplasia: Case Report

Milan Vrkljan
Marko Doko
Marijo Bekić
Branka Vizner
Mario Zovak
Josip Rešetić
Goran Roić
Mladen Belicza

Puni tekst: engleski pdf 455 Kb

str. 209-214

preuzimanja: 1.897



Hypoglycemia may occur as a component of type 1 multiple endocrine neoplasia syndrome. Insulinomas are rare tumors that often present a diagnostic dilemma for the clinician. The presence of inappropriately high plasma insulin and C-peptide concentrations at the time of symptomatic fasting hypoglycemia confirms the diagnosis of insulinoma. A. B., a 21-year-old girl, presented for evaluation of recurrent episodes of hyperhidrosis, confusion, and weakness with tremor, which was suggestive of hypoglycemia. Her body mass increased by 90 kg, with persistent symptoms of hypoglycemia. Because of her extremely excess sive body weight of 158 kg, the only diagnostic method available was upper abdomen ultrasonography, which revealed a tumor mass of 26 mm in size, located at the tail of the pancreas. Hemipancreatectomy and splenectomy were performed in one act. After the surgery, clinical symptoms disappeared but the patient developed diabetes, postoperatively, which required introduction of insulin therapy. Her body weight gradually normalized, she lost 54 kg, and postoperative magnetic resonance and computed tomography controls produced normal findings.

Ključne riječi

Multiple endocrine neoplasia type 1, diagnosis; Multiple endocrine neoplasia type 1, complications; Hypoglycemia, etiology; Case report

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Podaci na drugim jezicima: hrvatski

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