Veterinarski arhiv, Vol. 86 No. 2, 2016.
Izvorni znanstveni članak
Comparative therapeutic effect of antiseptic-antibiotic paste for topical treatment of digital dermatitis in dairy cows.
El-Sayed El-Shafaey
orcid.org/0000-0001-9463-7085
; Department of Surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura-city, Dakahlia, Egypt
Yousef Elseady
; Department of Physiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura-city, Dakahlia, Egypt
Sabry El-Khodery
; Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura-city, Dakahlia, Egypt
Sažetak
The present study was designed to evaluate the effificacy of the concomitant use of antiseptic paste with a reduced amount of broad spectrum antibiotic as an alternative topical treatment of digital dermatitis (DD) in dairy cows. Thirty Holstein-Friesian dairy cows with active DD lesions were selected randomly from 93 diseased cases. Cows were randomly allocated for three topical treatment trials (10 each) using antiseptic paste (3 g iodine, 2 g potassium iodine and 30 g zinc oxide/100 g), antibiotic paste (250 mg/ 3gm of cefazolin) and antiseptic-antibiotic paste, under a light bandage for 72 hours. The clinical index scores and case defifinition scores were assessed on day 0, pre-treatment, and at 7, 14, 21 and 28 days post-treatment. The group treated with antiseptic-antibiotic paste showed significantly decreased scores of lesion depth (P<0.05) and size (P<0.05) when compared with the groups treated with antiseptic or antibiotic paste on the 21 and 28 days posttreatment. Collectively, the summation of clinical index scores showed a significant decrease (P<0.05) in the group treated with the antiseptic-antibiotic combination compared with the antiseptic and antibiotic groups at 14 days post-treatment. By the 28th day, the recovery rates were 9/10, 5/10 and 4/10 for the groups treated with the antiseptic-antibiotic combination, antibiotic or antiseptic paste, respectively. In conclusion, our results suggest the clinically synergistic effect of the topical antiseptic-antibiotic combination, which appears to be an effective alternative treatment for DD in dairy cows, minimizing the amount of antibiotic residues.
Ključne riječi
antiseptic-antibiotic paste; case definition; clinical index; coows; digital dermatitis
Hrčak ID:
156707
URI
Datum izdavanja:
22.4.2016.
Posjeta: 1.155 *