Croatica Chemica Acta, Vol. 89 No. 1, 2016.
Original scientific paper
https://doi.org/10.5562/cca2599
Synthesis, Structural Analysis and Antimicrobial Activities of Novel Water Soluble Ionic Liquids Derived from N-Heterocyclic Carbene Salts
Ahmet Kunduracıoğlu
; Tavas Vocational College, Pamukkale University, Tavas-Denizli, Turkey
Özkan Gübe
; Bioengineering Dept. Engineering Faculty, Aegean University, Bornova-Izmir, Turkey
Elif Esin Hameş-Kocabaş
; Bioengineering Dept. Engineering Faculty, Aegean University, Bornova-Izmir, Turkey
Volkan Eyüpoğlu
; Çankırı Karatekin University, Faculty of Science, Çankırı, Turkey
Fatih Sönmez
; Pamukova Vocational College, Sakarya University, Pamukova- Sakarya, Turkey
Abstract
Six N-heterocyclic Carbene based Ionic Liquids (ILs) have been synthesized by conventional methods. The ILs were spectroscopically characterized by NMR and FT-IR techniques. Their in vitro antimicrobial activities were determined towards gram-positive and gram-negative bacterias and yeast strains using minimum inhibition concentration (MIC) assay. The best inhibition performances were obtained with compound 1 due to its more hydrophilic nature compared with the others. It exhibited 1 mg L–1 MIC value against to the most bacteria while the others showed 4 mg L–1.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Keywords
ionic liquids; <i>N</i>-heterocyclic carbenes; antimicrobial activity; <i>N</i>-functional substituents
Hrčak ID:
158797
URI
Publication date:
20.6.2016.
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