Veterinarski arhiv, Vol. 86 No. 3, 2016.
Izvorni znanstveni članak
Evaluation of the blood oxidant-antioxidant interactions in pigeons naturally infected with Haemoproteus columbae.
Seyed M. Razavi
; Department of Pathobiology and, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Saeed Nazifi
; Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Mina Afsar
; Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Zakieh Yazdanpanah
; Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Ehsan Rakhshandehroo
; Department of Pathobiology and, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Sažetak
Haemoproteus columbae is a haemosporidian parasite that infects pigeons throughout the world. The present study was designed to elucidate more aspects of the antioxidant defense of the body against haemoparasite infections in pigeons. A total of 46 indigenous pigeons naturally infected with H. columbae were selected and subdivided into three subgroups based on their parasitemia rates (<1 %, 1-3 %, 3-5 %). 24 non-infected birds were also used as controls. Blood samples from both groups were taken, and haematological parameters were measured. Although our data demonstrated significant decreases in the red blood cell count (RBC), packed cell volume (PCV) and haemoglobin values of the infected animals (P<0.05), no remarkable changes were observed in the activities of antioxidant enzymes (including superoxide dismutase (SOD), glutathione peroxidase (GPX) and catalase), the level of malondiadehyde (MDA) as an index of lipid peroxidation, serum levels of lipids (cholesterol, triglyceride, HDL and LDL) and serum concentrations of antioxidant trace elements (copper, iron, zinc, manganese and selenium) and vitamins (A, E and C) in infected groups compared to controls. These findings show that anaemia may occur as a result of the infection with H. columbae in pigeons. In addition, the unchanged levels of different antioxidant agents, lipid peroxidation index (MDA) and the main lipid components of serum during the infection, may implicitly suggest that the parasite probably cannot induce significant effects on the antioxidant mechanisms protecting erythrocytes against oxidative agents. Also, oxidative shock may not play a significant role in the pathogenesis of the parasite in pigeons infected with H. columbae. Further studies to clarify the exact mechanism(s) of anaemia in this haemoparasitic infection need to be carried out.
Ključne riječi
Haemoproteus columbae; antioxidant enzymes; malondialdehyde trace elements; antioxidant vitamins
Hrčak ID:
161265
URI
Datum izdavanja:
10.6.2016.
Posjeta: 1.022 *