Acta Pharmaceutica, Vol. 55 No. 2, 2005.
Izvorni znanstveni članak
Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifolium
LUTFUN NAHAR
WENDY R. RUSSELL
MOIRA MIDDLETON
MOHAMMAD SHOEB
SATYAJIT D. SARKER
Sažetak
Reversed-phase preparative HPLC analysis of the methanol extract of the seeds of Ilex aquifolium afforded two antioxidant phenylacetic acid derivatives, 2,4-dihydroxyphenylacetic acid (1) and 2,4-dihydroxyphenylacetic acid methyl ester (2). The structures were determined by spectroscopic methods. In the DPPH assay for antioxidant activity, the IC50 values of 1 and 2 were 1.50 x 10-3 and 2.55 x 10-3 mg mL-1, respectively, compared to 2.88 x 10-5 mg mL-1 of quercetin, a natural antioxidant.
Ključne riječi
Ilex aquifolium (Aquifoliaceae); phenylacetic acid derivatives; antioxidant; DPPH
Hrčak ID:
16756
URI
Datum izdavanja:
1.6.2005.
Posjeta: 3.478 *