Infektološki glasnik, Vol. 26 No. 3, 2006.
Izvorni znanstveni članak
Respiratory tract infections caused by Chlamydia trachomatis in newborns and infants
A. Baće
M. Perović
M. Balen-Topić
L. Markovinović
Sažetak
We retrospectively analyzed clinical, diagnostic and therapeutic characteristics of Chlamyda trachomatis infection in 46 newborns and infants hospitalized at the University Hospital for Infectious Diseases Zagreb between December 1994 and October 2005. The median age of patients was seven weeks. In 44/46 (95.6 %) children Chlamydia was demonstrated by using the DNA-RNA hybridisation method, and in the remaining by cell culture (McCoy). Chlamydia was mostly isolated from a nasal aspirate. Altogether 16/46 (34.7 %) children had Chlamyda trachomatis monoinfection and the rest had a co-infection, mostly with RSV. On admission, the majority of children were febrile and had the following respiratory symptoms: dry cough, nasal secretion and conjunctival infection. Because of poor general condition, five patients were mechanically ventilated. Concerning laboratory characteristics, 4/16 (25.0 %) children with monoinfection had eosinophilia, and 13/16 (81.3 %) hypergammaglobulinaemia. In total, 27/46 (58.7 %) children were treated with azithromycin, and 19/46 (41.3 %) with erythromycin. The children treated with azithromycin were hospitalized for 13.9 days, and the children treated with erythromycin for 22.6 days. All children recovered successfully.
Ključne riječi
Clamydia trachomatis; pneumonia; conjuctivitis; RSV; B. pertussis
Hrčak ID:
12686
URI
Datum izdavanja:
14.9.2006.
Posjeta: 2.954 *