Pregledni rad

https://doi.org/10.18054/pb.v118i4.4846

PKA and the Structural Kinome

Susan S. Taylor ; Department of Pharmacology and Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, CA 92093
Alexandr P. Kornev ; Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093

Sažetak

In recognition of the first protein kinase structure that was solved 25 years ago, we review the history of the Structural Kinome. What did we learn prior to that first structure of the PKA catalytic subunit, what have we learned since the structure was solved, and what are our remaining challenges for the future?

Ključne riječi

Hrčak ID:

177556

URI

https://hrcak.srce.hr/177556

Datum izdavanja:

17.3.2017.

Posjeta: 1.657 *