Izvorni znanstveni članak

Mixed Anhydrides of Penicillinic and Cephalosporinic Acids with N-Acyl Carbamic Acid

Miće Kovačević ; Research Institute PLIVA, Zagreb, Croatia, Yugoslavia
Jure J. Herak ; Research Institute PLIVA, Zagreb, Croatia, Yugoslavia
Branimir Gašpert ; Research Institute PLIVA, Zagreb, Croatia, Yugoslavia

Sažetak

Mixed anhydrides with penicillinic acids (III) were unstable and gave N-acyl, amides IV. Only III with butyrolactam was stable and reacted with alcohols to give esters V. All anhydrides with cephalosporinic acids (VIlI) yielded symmetric anhydrides IX. Alcoholysis of IX gave cephalosporinic ester X, while aminolysis yielded amide. Formation of postulated isomeric mixed anhydride with O-imino carbonic acid ester XlIIb is discussed.

Ključne riječi

Hrčak ID:

177771

URI

https://hrcak.srce.hr/177771

Datum izdavanja:

31.10.1985.

Posjeta: 861 *