Infektološki glasnik, Vol. 36 No. 1, 2016.
Pregledni rad
Current roles of microRNAs in infectious diseases – advancing into healthcare
Juan Joze Gonzalez Plaza
; Znanstvena jedinica, Klinika za infektivne bolesti
Sažetak
Among all new emerging RNA species, microRNAs (miRNAs) have attracted the interest of the scientific community due to their implications as biomarkers of prognostic value, disease progression, or diagnosis, because of defining features as robust association with the disease, or stable presence in easily accessible human biofluids. This field of research has been established twenty years ago, and the development has been considerable. The regulatory nature of miRNAs makes them great candidates for the treatment of infectious diseases, and a successful example in the field is currently being translated to clinical practice. This review will present a general outline of miRNA molecules, as well as successful stories of translational significance which are getting us closer from the basic bench studies into clinical practice.
Ključne riječi
MicroRNA; infectious diseases; viruses; bacteria; pathogen; biomarkers
Hrčak ID:
182345
URI
Datum izdavanja:
31.3.2016.
Posjeta: 2.719 *