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Current roles of microRNAs in infectious diseases – advancing into healthcare

Juan Joze Gonzalez Plaza ; Znanstvena jedinica, Klinika za infektivne bolesti


Puni tekst: hrvatski pdf 273 Kb

str. 5-15

preuzimanja: 1.224

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Sažetak

Among all new emerging RNA species, microRNAs (miRNAs) have attracted the interest of the scientific community due to their implications as biomarkers of prognostic value, disease progression, or diagnosis, because of defining features as robust association with the disease, or stable presence in easily accessible human biofluids. This field of research has been established twenty years ago, and the development has been considerable. The regulatory nature of miRNAs makes them great candidates for the treatment of infectious diseases, and a successful example in the field is currently being translated to clinical practice. This review will present a general outline of miRNA molecules, as well as successful stories of translational significance which are getting us closer from the basic bench studies into clinical practice.

Ključne riječi

MicroRNA; infectious diseases; viruses; bacteria; pathogen; biomarkers

Hrčak ID:

182345

URI

https://hrcak.srce.hr/182345

Datum izdavanja:

31.3.2016.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.062 *