Veterinarski arhiv, Vol. 87 No. 4, 2017.
Izvorni znanstveni članak
https://doi.org/10.24099/vet.arhiv.160408a
Characterization of turtle demineralized bone matrix (DBM) and turtle bone in rat radial bone defects; radiological, histopathological, biomechanical and scanning electron microscopic evaluation
Ahmad Oryan
; Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Amin Bigham-Sadegh
orcid.org/0000-0003-4981-7495
; Department of Veterinary Surgery and Radiology, Faculty of Veterinary Medicine, Shahr-e-Kord University, Shahr-e-Kord, Iran
Somayeh Monazzah
; Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Sažetak
Bone grafts are used to treat various disorders, including delayed union and nonunion of fractures, congenital pseudoarthrosis, and osseous defects from trauma, infection, and tumors. The disadvantages of allografts, such as disease transmission, have led to the exploration of xenografts as an alternative grafting material. We used turtle DBM and turtle bone grafts in this study. A critical size defect of 2.5 times diameter elongation was created in the radial diaphysis of 16 rats in this study. The rats were divided into 4 groups: defect as control˗, autograft as control+, turtle bone and turtle DBM. The results of radiological, histopathological, biomechanical and scanning electron microscopic evaluation of groups were compared. The biomechanical and radiological evaluation shows that there was no significant difference between groups; but histopathological evaluation shows significant differences between groups in union and cancellous bone. The turtle DBM group had the same result as control+ and was superior to the other groups.
Ključne riječi
fracture healing; xenograft; turtle bone; turtle demineralized bone matrix; Rat model
Hrčak ID:
185678
URI
Datum izdavanja:
3.7.2017.
Posjeta: 1.255 *