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https://doi.org/10.20471/acc.2017.56.02.01

Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction

Bojan Sudarević ; Department of Urology, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of Osijek
Ivana Begić ; Department of Dialysis, Clinical Department of Internal Medicine, Osijek University Hospital Center; Department of Physiology and Immunology, School of Medicine, Josip Juraj Strossmayer University of Osijek
Dalibor Šimunović ; Department of Urology, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of Osijek
Hrvoje Kuveždić ; Department of Urology, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of Osijek
Vatroslav Šerić ; Department of Clinical Laboratory Diagnosis, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of Osijek
Lada Zibar ; Department of Dialysis, Clinical Department of Internal Medicine, Osijek University Hospital Center; Department of Pathophysiology, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia


Puni tekst: engleski pdf 83 Kb

str. 195-202

preuzimanja: 854

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Sažetak

Erectile dysfunction (ED) is a highly prevalent disorder among renal transplant recipients. Vitamin D deficiency (VDD) has been associated with several ED risk factors but only recently directly linked to ED. We conducted a study to investigate whether vitamin D serum levels were associated with the presence and severity of ED in 40 male patients that underwent deceased donor kidney transplantation (TX) from 2001 to 2013. Blood samples were collected on two seasonally distinct occasions and 25(OH)D concentration was assessed by radioimmunoassay. A 5-item version of the International Index of Erectile Function (IIEF-5) was used for ED evaluation and group stratification. We found comparable rates of ED (75%) and VDD (42.5%-62.5%) as in previously published studies. Serum levels of 25(OH)D did not differ between patients with and those without ED on both measurements (p=0.656 and p=0.914, respectively), or when comparing different ED severity groups. Duration of renal replacement therapy before TX and graft duration until analysis were longer in patients with ED (p=0.022 and p=0.05, respectively), but with the results being nonsignificant on logistic regression. In conclusion, we found no association of 25(OH)D concentration with the presence and severity of ED in renal transplant recipients. So far, there are no similar published data.

Ključne riječi

Vitamin D deficiency; Erectile dysfunction; Endothelium, vascular; Renal insufficiency, chronic; Kidney transplantation; Croatia

Hrčak ID:

186382

URI

https://hrcak.srce.hr/186382

Datum izdavanja:

1.6.2017.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.380 *