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Clinical characteristic of campylobacteriosis in hospitalised patients

M. Balen Topić
A. Beus
B. Desnica
N. Vicković
V. Šimić
D. Šimić

Sažetak

Diseases caused by gram-negative bacteria from genus Campylobacter in humans are most often presented as an acute diarrhoeal illness, which lasts up to seven days. Complications are rare, and among them the most important are: sepsis, bacteremia with extraintestinal sites of infection, septic abortion, and immunologically triggered Guillain-Barré syndrome. Among 1632 hospitally treated patients in the period from 1994–2002, the analysis of a particular clinical parameters using logistic regression showed significantly longer duration of diarrhoea among patients with C. jejuni infection (p = 0.014, OR 1.06, 95 % CI 1.01–1.11). Disease complications were observed in 4.6 % patients, and no fatalities or hospitalisations of observed patients due to Guillain-Barré syndrome in any of the hospitals from Zagreb region were recorded. Complications were significantly more frequent (7.2 %) in the age group younger than three years (p = 0.010). Adequate antimicrobial treatment received 78.7 % of patients, unadequate antimicrobial treatment 6.7 %, and 14.6 % of patients were treated symptomaticaly. Clinical characteristics in our patients with campylobacteriosis do not differ significantly from those described in populations of developed countries. As a peculiarity, a common use of antimicrobial therapy is recorded, and azithromycin, used in 46.4 % of patients treated with adequate antimicrobial treatment, was the most frequently used drug.

Ključne riječi

campylobacteriosis; clinical charcteristics; hospitalised patients

Hrčak ID:

17841

URI

https://hrcak.srce.hr/17841

Datum izdavanja:

30.6.2007.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.366 *