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PURE RED BLOOD CELL APLASIA IN SYSTEMIC LUPUS ERYTHEMATOSUS – A CASE REPORT

Marija Tomac-Stojmenović
Ita Hadžisejdić
Toni Valković
Srđan Novak


Puni tekst: hrvatski pdf 152 Kb

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Sažetak

Acquired pure red cell aplasia (PRCA) is a rare, generally chronic condition of profound anemia characterized by
a severe reduction in the number of reticulocytes in the peripheral blood and the virtual absence of erythroid precursors
in the bone marrow. All other cell lineages are present and appear morphologically normal. In systemic lupus
erythematosus (SLE) red cell aplasia is probably due to antibodies directed against either erythropoietin or bone marrow
erythroblasts. Th is form of anemia usually responds to steroids, although cyclophosphamide and cyclosporine
have been successfully employed as well. We present the case of a patient with PRCA in SLE.

Ključne riječi

Lupus erythematosus, systemic – complications, drug therapy, immunology, Red-cell aplasia, pure – diagnosis, drug therapy, etiology, immunology, Autoantibodies – immunology, Erythropoiesis – immunology, Cyclosporine – administration and dosage, therapeutic use, Methylprednisolone – administration and dosage, therapeutic use

Hrčak ID:

188324

URI

https://hrcak.srce.hr/188324

Podaci na drugim jezicima: hrvatski

Posjeta: 1.196 *