Infektološki glasnik, Vol. 25 No. 2, 2005.
Stručni rad
Clinical and epidemiological characteristics of Q fever in hospitalized patients
I. Puljiz
I. Kuzman
O. Đaković-Rode
Sažetak
We retrospectively analysed clinical and epidemiological characteristics of Q fever in 25 patients hospitalized at the University Hospital for Infectious Diseases in Zagreb from January 1 to December 31, 2004. The diagnosis of Q fever was confirmed by serology in all patients, by an enzyme-linked immunosorbent assay (ELISA). The disease occurred from March to July. All patients were sporadic cases, and they were inhabitants of Zagreb and its surrounding areas. Thirteen (52.0 %) patients with Q fever were infected in their place of living, 10 (40.0 %) in other parts of Croatia, while 2 (8.0 %) patients were in Bosnia and Hercegovina during the incubation period. There were significantly more males than females (22:3). Most of the patients (68.0 %) were aged 21–40 years. Main symptoms of disease were fever, headache, and cough, and most significant pathological laboratory findings were accelerated erythrocyte sedimentation rate and increased value of C- reactive protein. Chest X-ray revealed interstitial pulmonary infiltrates in the majority of patients, localized in a single pulmonary lobe (23 or 92.0 %). Pleural effusion was recorded in 2 (8.0 %) patients. The patients were treated with azithromycin, fluoroquinolone, and doxycycline. Doxycycline showed the best clinical efficacy. All patients were cured.
Ključne riječi
Q-fever; clinical characteristics; epidemiology; Croatia
Hrčak ID:
12755
URI
Datum izdavanja:
25.5.2005.
Posjeta: 2.887 *